KSR2 antibody (AA 411-500)

Catalog No. ABIN567007

This Mouse Monoclonal antibody specifically detects KSR2 in ELISA, WB and RNAi. It exhibits reactivity toward Human and has been mentioned in 2+ publications.

Quick Overview for KSR2 antibody (AA 411-500) (ABIN567007)

Target: KSR2 (Kinase Suppressor of Ras 2 (KSR2))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This KSR2 antibody is un-conjugated

Application: ELISA, Western Blotting (WB), RNA Interference (RNAi)

Clone: 1G4

Product Details anti-KSR2 Antibody

Binding Specificity: AA 411-500

Purpose: Mouse monoclonal antibody raised against a partial recombinant KSR2.

Sequence: PAPPLPPSAT PPSPLHPSPQ CTRQQKNFNL PASHYYKYKQ QFIFPDVVPV PETPTRAPQV ILHPVTSNPI LEGNPLLQIE VEPTSENEEV

Cross-Reactivity: Human

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: KSR2 (NP_775869, 411 a.a. ~ 500 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Isotype: IgG2b

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-KSR2 antibody (ABIN567007)

Fernandez, Henry, Lewis: "Kinase suppressor of Ras 2 (KSR2) regulates tumor cell transformation via AMPK." in: Molecular and cellular biology, Vol. 32, Issue 18, pp. 3718-31, (2012) (PubMed).

Costanzo-Garvey, Pfluger, Dougherty, Stock, Boehm, Chaika, Fernandez, Fisher, Kortum, Hong, Jun, Ko, Schreiner, Volle, Treece, Swift, Winer, Chen, Wu, Leon, Shaw, McNeish, Kim, Morrison, Tschöp, Lewis: "KSR2 is an essential regulator of AMP kinase, energy expenditure, and insulin sensitivity." in: Cell metabolism, Vol. 10, Issue 5, pp. 366-78, (2009) (PubMed).

Target Details for KSR2

Target: KSR2 (Kinase Suppressor of Ras 2 (KSR2))

Alternative Name: KSR2

Background: Full Gene Name: kinase suppressor of ras 2
Synonyms: FLJ25965

Gene ID: 283455

NCBI Accession: NM_173598