Protein Phosphatase PP2A 55 kDa Regulatory Subunit (N-Term) antibody

Catalog No. ABIN5671352

The Rabbit Polyclonal anti-Protein Phosphatase PP2A 55 kDa Regulatory Subunit antibody (ABIN5671352) specifically detects Protein Phosphatase PP2A 55 kDa Regulatory Subunit in WB. The antibody is reactive with Human samples.

Quick Overview for Protein Phosphatase PP2A 55 kDa Regulatory Subunit (N-Term) antibody (ABIN5671352)

Target: Protein Phosphatase PP2A 55 kDa Regulatory Subunit

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Application: Western Blotting (WB)

Product Details

Binding Specificity: N-Term

Sequence: SERDKRPEGY NLKEEDGRYR DPTTVTTLRV PVFRPMDLMV EASPRRIFAN

Characteristics: This is a rabbit polyclonal antibody against 2ABA. It was validated on Western Blot.

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human 2ABA

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details

Target: Protein Phosphatase PP2A 55 kDa Regulatory Subunit

Alternative Name: 2ABA

Background: The product of this gene belongs to the phosphatase 2 regulatory subunit B family. Protein phosphatase 2 is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The B regulatory subunit might modulate substrate selectivity and catalytic activity. This gene encodes an alpha isoform of the regulatory subunit B55 subfamily. Alternatively spliced transcript variants have been described.

Alias Symbols: PPP2R2A,

Protein Interaction Partner: PPP2R1A, UBC, Fbxl16, rev, NRD1, CACNA1S, HSPA4L, THUMPD1, PPP3CA, CDK17, CDK16, LATS2, EGFR, HDAC5, GRB2, CFTR, SMURF1, NOTCH1, PPP2CA, PPP2R1B, GRK5, CUL3, PTPN14, ELAVL1, SUMO1, NDRG1, PPP2R2D, CDCA4, SKIV2L2, CCT5, CCT8, CCT2, CCT4, CCT7, TUBA4A, CCT3

Protein Size: 447

Gene ID: 5520

NCBI Accession: NP_002708

UniProt: P63151