Periaxin antibody (C-Term)

Catalog No. ABIN5671378

The Rabbit Polyclonal anti-Periaxin antibody is suitable to detect Periaxin in samples from Human. It has been validated for WB.

Quick Overview for Periaxin antibody (C-Term) (ABIN5671378)

Target: Periaxin (PRX)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Periaxin antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Periaxin Antibody

Binding Specificity: C-Term

Purpose: PRX Antibody - C-terminal region

Sequence: SRGQEGDAAP KSPVREKSPK FRFPRVSLSP KARSGSGDQE EGGLRVRLPS

Characteristics: This is a rabbit polyclonal antibody against PRAX. It was validated on Western Blot.

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human PRAX

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP75716-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for Periaxin

Target: Periaxin (PRX)

Alternative Name: PRX

Background:

Background Information: This gene encodes a protein involved in peripheral nerve myelin upkeep. The encoded protein contains 2 PDZ domains which were named after PSD95 (post synaptic density protein), DlgA (Drosophila disc large tumor suppressor), and ZO1 (a mammalian tight junction protein). Two alternatively spliced transcript variants have been described for this gene which encode different protein isoforms and which are targeted differently in the Schwann cell. Mutations in this gene cause Charcot-Marie-Tooth neuoropathy, type 4F and Dejerine-Sottas neuropathy.

Gene Name: periaxin

Alternative Symbols: CMT4F

Protein Name: periaxin

Molecular Weight: 145kDa

Gene ID: 57716

UniProt: Q9BXM0