FKBP5 antibody (N-Term)

Catalog No. ABIN5671411

The Rabbit Polyclonal anti-FKBP5 antibody is suitable to detect FKBP5 in samples from Human. It has been validated for WB.

Quick Overview for FKBP5 antibody (N-Term) (ABIN5671411)

Target: FKBP5 (FK506 Binding Protein 5 (FKBP5))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FKBP5 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-FKBP5 Antibody

Binding Specificity: N-Term

Sequence: SNGKKFDSSH DRNEPFVFSL GKGQVIKAWD IGVATMKKGE ICHLLCKPEY

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human FKBP5

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for FKBP5

Target: FKBP5 (FK506 Binding Protein 5 (FKBP5))

Alternative Name: FKBP5

Background: The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds to the immunosuppressants FK506 and rapamycin. It is thought to mediate calcineurin inhibition. It also interacts functionally with mature hetero-oligomeric progesterone receptor complexes along with the 90 kDa heat shock protein and P23 protein. This gene has been found to have multiple polyadenylation sites. Alternative splicing results in multiple transcript variants.

Alias Symbols: P54, AIG6, FKBP51, FKBP54, PPIase, Ptg-10

Protein Size: 457

Gene ID: 2289

NCBI Accession: NM_001145775, NP_001139247

UniProt: Q13451