MRAS antibody (C-Term)

Catalog No. ABIN5671693

The Rabbit Polyclonal anti-MRAS antibody (ABIN5671693) specifically detects MRAS in WB. The antibody is reactive with Human samples.

Quick Overview for MRAS antibody (C-Term) (ABIN5671693)

Target: MRAS (Muscle RAS Oncogene Homolog (MRAS))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MRAS antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-MRAS Antibody

Binding Specificity: C-Term

Sequence: PYIETSAKDP PLNVDKAFHD LVRVIRQQIP EKSQKKKKKT KWRGDRATGT

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of Human MRAS

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for MRAS

Target: MRAS (Muscle RAS Oncogene Homolog (MRAS))

Alternative Name: MRAS

Background: This gene encodes a member of the Ras family of small GTPases. These membrane-associated proteins function as signal transducers in multiple processes including cell growth and differentiation, and dysregulation of Ras signaling has been associated with many types of cancer. The encoded protein may play a role in the tumor necrosis factor-alpha and MAP kinase signaling pathways. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Alias Symbols: M-RAs, RRAS3, R-RAS3

Protein Size: 208

Gene ID: 22808

NCBI Accession: NM_001085049, NP_001078518

UniProt: O14807