Keratin 6B antibody (C-Term)

Catalog No. ABIN5672206

This Rabbit Polyclonal antibody specifically detects Keratin 6B in WB. It exhibits reactivity toward Human.

Quick Overview for Keratin 6B antibody (C-Term) (ABIN5672206)

Target: Keratin 6B (KRT6B)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Keratin 6B antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Keratin 6B Antibody

Binding Specificity: C-Term

Sequence: SSGYGGASGV GSGLGLGGGS SYSYGSGLGV GGGFSSSSGR ATGGGLSSVG

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human KRT6B

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for Keratin 6B

Target: Keratin 6B (KRT6B)

Alternative Name: KRT6B

Background: The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. As many as six of this type II cytokeratin (KRT6) have been identified, the multiplicity of the genes is attributed to successive gene duplication events. The genes are expressed with family members KRT16 and/or KRT17 in the filiform papillae of the tongue, the stratified epithelial lining of oral mucosa and esophagus, the outer root sheath of hair follicles, and the glandular epithelia. Mutations in these genes have been associated with pachyonychia congenita. The type II cytokeratins are clustered in a region of chromosome 12q12-q13.

Alias Symbols: K6B, PC2, PC4, CK6B, CK-6B, KRTL1

Protein Size: 564

Gene ID: 3854

NCBI Accession: NM_005555, NP_005546

UniProt: P04259