BHMT2 antibody (C-Term)

Catalog No. ABIN5672902

The Rabbit Polyclonal anti-BHMT2 antibody is suitable to detect BHMT2 in samples from Human. It has been validated for WB.

Quick Overview for BHMT2 antibody (C-Term) (ABIN5672902)

Target: BHMT2 (Betaine--Homocysteine S-Methyltransferase 2 (BHMT2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BHMT2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-BHMT2 Antibody

Binding Specificity: C-Term

Sequence: RYIGGCCGFE PYHIRAIAEE LAPERGFLPP ASEKHGSWGS GLDMHTKPWI

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human BHMT2

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for BHMT2

Target: BHMT2 (Betaine--Homocysteine S-Methyltransferase 2 (BHMT2))

Alternative Name: BHMT2

Background: Homocysteine is a sulfur-containing amino acid that plays a crucial role in methylation reactions. Transfer of the methyl group from betaine to homocysteine creates methionine, which donates the methyl group to methylate DNA, proteins, lipids, and other intracellular metabolites. The protein encoded by this gene is one of two methyl transferases that can catalyze the transfer of the methyl group from betaine to homocysteine. Anomalies in homocysteine metabolism have been implicated in disorders ranging from vascular disease to neural tube birth defects such as spina bifida. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Protein Size: 406

Gene ID: 23743

NCBI Accession: NM_001178005, NP_001171476

UniProt: Q93088

Pathways: Methionine Biosynthetic Process