14-3-3 gamma antibody (C-Term)

Catalog No. ABIN5673008

The Rabbit Polyclonal anti-14-3-3 gamma antibody (ABIN5673008) specifically detects 14-3-3 gamma in WB. The antibody is reactive with Human samples.

Quick Overview for 14-3-3 gamma antibody (C-Term) (ABIN5673008)

Target: 14-3-3 gamma (YWHAG1)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This 14-3-3 gamma antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-14-3-3 gamma Antibody

Binding Specificity: C-Term

Sequence: KTAFDDAIAE LDTLNEDSYK DSTLIMQLLR DNLTLWTSDQ QDDDGGEGNN

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human YWHAG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for 14-3-3 gamma

Target: 14-3-3 gamma (YWHAG1)

Alternative Name: YWHAG

Background: This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 100 % identical to the rat ortholog. It is induced by growth factors in human vascular smooth muscle cells, and is also highly expressed in skeletal and heart muscles, suggesting an important role for this protein in muscle tissue. It has been shown to interact with RAF1 and protein kinase C, proteins involved in various signal transduction pathways.

Alias Symbols: PPP1R170, 14-3-3GAMMA

Protein Size: 247

Gene ID: 7532

NCBI Accession: NM_012479, NP_036611

UniProt: P61981

Pathways: Myometrial Relaxation and Contraction, M Phase