NPAT antibody (Middle Region)

Catalog No. ABIN5673429

This Rabbit Polyclonal antibody specifically detects NPAT in WB. It exhibits reactivity toward Human.

Quick Overview for NPAT antibody (Middle Region) (ABIN5673429)

Target: NPAT (Nuclear Protein, Ataxia-Telangiectasia Locus (NPAT))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NPAT antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-NPAT Antibody

Binding Specificity: Middle Region

Sequence: TPPEGTPVEN SHSLPPESVC SSVGDSHPES QNTDDKPSSN NSAEIDASNI

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human NPAT

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for NPAT

Target: NPAT (Nuclear Protein, Ataxia-Telangiectasia Locus (NPAT))

Alternative Name: NPAT

Background: Required for progression through the G1 and S phases of the cell cycle and for S phase entry. Activates transcription of the histone H2A, histone H2B, histone H3 and histone H4 genes in conjunction with MIZF. Also positively regulates the ATM, MIZF and PRKDC promoters. Transcriptional activation may be accomplished at least in part by the recruitment of the NuA4 histone acetyltransferase (HAT) complex to target gene promoters.

Alias Symbols: E14, p220, E14/NPAT

Protein Size: 1427

Gene ID: 4863

NCBI Accession: NM_002519, NP_002510

UniProt: Q14207