SEC24D antibody (N-Term)

Catalog No. ABIN5673506

This anti-SEC24D antibody is a Rabbit Polyclonal antibody detecting SEC24D in WB. Suitable for Human.

Quick Overview for SEC24D antibody (N-Term) (ABIN5673506)

Target: SEC24D (SEC24 Family, Member D (S. Cerevisiae) (SEC24D))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SEC24D antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-SEC24D Antibody

Binding Specificity: N-Term

Sequence: PPGPPPPGPH QFGQNGAHAT GHPPQRFPGP PPVNNVASSH APYQPSAQSS

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human SEC24D

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for SEC24D

Target: SEC24D (SEC24 Family, Member D (S. Cerevisiae) (SEC24D))

Alternative Name: SEC24D

Background: The protein encoded by this gene is a member of the SEC24 subfamily of the SEC23/SEC24 family, which is involved in vesicle trafficking. The encoded protein has similarity to yeast Sec24p component of COPII. COPII is the coat protein complex responsible for vesicle budding from the ER. This gene product is implicated in the shaping of the vesicle, and also in cargo selection and concentration. Mutations in this gene have been associated with Cole-Carpenter syndrome, a disorder affecting bone formation, resulting in craniofacial malformations and bones that break easily. Alternative splicing results in multiple transcript variants encoding different isoforms.

Alias Symbols: CLCRP2

Protein Size: 1032

Gene ID: 9871

NCBI Accession: NM_001318066, NP_001304995

UniProt: O94855