SEC24D antibody (AA 830-1000)

Catalog No. ABIN7270171

This Rabbit Polyclonal antibody specifically detects SEC24D in WB and IF. It exhibits reactivity toward Human.

Quick Overview for SEC24D antibody (AA 830-1000) (ABIN7270171)

Target: SEC24D (SEC24 Family, Member D (S. Cerevisiae) (SEC24D))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SEC24D antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Product Details anti-SEC24D Antibody

Binding Specificity: AA 830-1000

Purpose: SEC24D Rabbit pAb

Sequence: AASQLILPDS MKVLPVYMNC LLKNCVLLSR PEISTDERAY QRQLVMTMGV ADSQLFFYPQ LLPIHTLDVK STMLPAAVRC SESRLSEEGI FLLANGLHMF LWLGVSSPPE LIQGIFNVPS FAHINTDMTL LPEVGNPYSQ QLRMIMGIIQ QKRPYSMKLT IVKQREQPEM V

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 830-1000 of human SEC24D (NP_001304995.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for SEC24D

Target: SEC24D (SEC24 Family, Member D (S. Cerevisiae) (SEC24D))

Alternative Name: SEC24D

Background: The protein encoded by this gene is a member of the SEC24 subfamily of the SEC23/SEC24 family, which is involved in vesicle trafficking. The encoded protein has similarity to yeast Sec24p component of COPII. COPII is the coat protein complex responsible for vesicle budding from the ER. This gene product is implicated in the shaping of the vesicle, and also in cargo selection and concentration. Mutations in this gene have been associated with Cole-Carpenter syndrome, a disorder affecting bone formation, resulting in craniofacial malformations and bones that break easily. Alternative splicing results in multiple transcript variants encoding different isoforms.,SEC24D,CLCRP2,Signal Transduction,SEC24D

Molecular Weight: 113kDa

Gene ID: 9871

UniProt: O94855