TMEM43 antibody (N-Term)

Catalog No. ABIN5673734

The Rabbit Polyclonal anti-TMEM43 antibody (ABIN5673734) specifically detects TMEM43 in WB. The antibody is reactive with Human samples.

Quick Overview for TMEM43 antibody (N-Term) (ABIN5673734)

Target: TMEM43 (Transmembrane Protein 43 (TMEM43))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TMEM43 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-TMEM43 Antibody

Binding Specificity: N-Term

Sequence: ANYSSTSTRR EHVKVKTSSQ PGFLERLSET SGGMFVGLMA FLLSFYLIFT

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human TMEM43

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for TMEM43

Target: TMEM43 (Transmembrane Protein 43 (TMEM43))

Alternative Name: TMEM43

Background: This gene belongs to the TMEM43 family. Defects in this gene are the cause of familial arrhythmogenic right ventricular dysplasia type 5 (ARVD5), also known as arrhythmogenic right ventricular cardiomyopathy type 5 (ARVC5). Arrhythmogenic right ventricular dysplasia is an inherited disorder, often involving both ventricles, and is characterized by ventricular tachycardia, heart failure, sudden cardiac death, and fibrofatty replacement of cardiomyocytes. This gene contains a response element for PPAR gamma (an adipogenic transcription factor), which may explain the fibrofatty replacement of the myocardium, a characteristic pathological finding in ARVC.

Alias Symbols: LUMA, ARVC5, ARVD5, EDMD7

Protein Size: 400

Gene ID: 79188

NCBI Accession: NM_024334, NP_077310

UniProt: Q9BTV4