FAM57A antibody (Middle Region)

Catalog No. ABIN5673967

The Rabbit Polyclonal anti-FAM57A antibody is suitable to detect FAM57A in samples from Human. It has been validated for WB.

Quick Overview for FAM57A antibody (Middle Region) (ABIN5673967)

Target: FAM57A (Family with Sequence Similarity 57, Member A (FAM57A))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FAM57A antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-FAM57A Antibody

Binding Specificity: Middle Region

Sequence: ELSTPFVSLG RVLIQLKQQH TLLYKVNGIL TLATFLSCRI LLFPFMYWSY

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human FAM57A

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for FAM57A

Target: FAM57A (Family with Sequence Similarity 57, Member A (FAM57A))

Alternative Name: FAM57A

Background: The protein encoded by this gene is a membrane-associated protein that promotes lung carcinogenesis. The encoded protein may be involved in amino acid transport and glutathione metabolism since it can interact with a solute carrier family member (SLC3A2) and an isoform of gamma-glutamyltranspeptidase-like 3. An alternatively spliced variant encoding a protein that lacks a 32 aa internal segment showed the opposite effect, inhibiting lung cancer cell growth. Knockdown of this gene also inhibited lung carcinogenesis and tumor cell growth. Several transcript variants encoding different isoforms have been found for this gene.

Alias Symbols: CT120

Protein Size: 225

Gene ID: 79850

NCBI Accession: NM_024792, NP_079068