HYPK antibody (Middle Region)
Quick Overview for HYPK antibody (Middle Region) (ABIN5673969)
Target
Reactivity
Host
Clonality
Application
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Binding Specificity
- Middle Region
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Sequence
- DVELELETET SGPERPPEKP RKHDSGAADL ERVTDYAEEK EIQSSNLETA
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Purification
- Affinity purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of mouse HYPK
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- HYPK (Huntingtin Interacting Protein K (HYPK))
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Alternative Name
- HYPK
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Background
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Has a chaperone-like activity preventing polyglutamine (polyQ) aggregation of HTT. Protects against HTT polyQ-mediated apoptosis in neuronal cells. Required for optimal NAA10-NAA15 complex-mediated N-terminal acetylation (By similarity).
Alias Symbols: HSPC136, 2310003F16Rik
Protein Size: 129 -
Gene ID
- 67693
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NCBI Accession
- NM_026318, NP_080594
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UniProt
- Q9CR41
Target
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