Tumor Protein p73 antibody (C-Term)

Catalog No. ABIN5673992

This anti-Tumor Protein p73 antibody is a Rabbit Polyclonal antibody detecting Tumor Protein p73 in WB. Suitable for Human.

Quick Overview for Tumor Protein p73 antibody (C-Term) (ABIN5673992)

Target: Tumor Protein p73 (TP73) (Tumor Protein P73 (TP73))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Tumor Protein p73 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Tumor Protein p73 Antibody

Binding Specificity: C-Term

Sequence: NAATISIGGS GELQRQRVME AVHFRVRHTI TIPNRGGPGG GPDEWADFGF

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human TP73

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for Tumor Protein p73

Target: Tumor Protein p73 (TP73) (Tumor Protein P73 (TP73))

Alternative Name: TP73

Background: This gene encodes a member of the p53 family of transcription factors involved in cellular responses to stress and development. It maps to a region on chromosome 1p36 that is frequently deleted in neuroblastoma and other tumors, and thought to contain multiple tumor suppressor genes. The demonstration that this gene is monoallelically expressed (likely from the maternal allele), supports the notion that it is a candidate gene for neuroblastoma. Many transcript variants resulting from alternative splicing and/or use of alternate promoters have been found for this gene, but the biological validity and the full-length nature of some variants have not been determined.

Alias Symbols: P73

Protein Size: 565

Gene ID: 7161

NCBI Accession: NM_001126240, NP_001119712

Pathways: Regulation of Cell Size, Positive Regulation of Response to DNA Damage Stimulus