TESPA1 antibody (AA 231-330)

Catalog No. ABIN5675752

Product Details anti-TESPA1 Antibody

Target: TESPA1 (Thymocyte Expressed, Positive Selection Associated 1 (TESPA1))

Binding Specificity: AA 231-330

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TESPA1 antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Cross-Reactivity: Human

Predicted Reactivity: Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human TESPA1

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for TESPA1

Target: TESPA1 (Thymocyte Expressed, Positive Selection Associated 1 (TESPA1))

Alternative Name: TESPA1 (TESPA1 Products)

Synonyms: KIAA0748 antibody, thymocyte expressed, positive selection associated 1 antibody, TESPA1 antibody

Background:

Synonyms: Protein TESPA1, TESPA1, Thymocyte-expressed positive selection-associated protein 1, KIAA0748, HSPC257

Background: Required for the development and maturation of T-cells, its function being essential for the late stages of thymocyte development (By similarity). Plays a role in T-cell antigen receptor (TCR)-mediated activation of the ERK and NFAT signaling pathways, possibly by serving as a scaffolding protein that promotes the assembly of the LAT signalosome in thymocytes. May play a role in the regulation of inositol 1,4,5-trisphosphate receptor-mediated Ca2+ release and mitochondrial Ca2+ uptake via the mitochondria-associated endoplasmic reticulum membrane (MAM) compartment.

Gene ID: 9840

UniProt: A2RU30