EXD2 antibody (AA 351-621) (FITC)

Catalog No. ABIN5675768

This anti-EXD2 antibody is a Rabbit Polyclonal antibody detecting EXD2 in WB, IF (cc) and IF (p). Suitable for Human, Mouse and Rat.

Quick Overview for EXD2 antibody (AA 351-621) (FITC) (ABIN5675768)

Target: EXD2 (Exonuclease 3'-5' Domain Containing 2 (EXD2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EXD2 antibody is conjugated to FITC

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-EXD2 Antibody (FITC)

Binding Specificity: AA 351-621

Specificity: WB shows isoform 2

Cross-Reactivity: Human, Mouse, Rat

Predicted Reactivity: Dog,Cow,Sheep,Pig,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human EXD2

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for EXD2

Target: EXD2 (Exonuclease 3'-5' Domain Containing 2 (EXD2))

Alternative Name: EXD2

Background:

Synonyms: Exonuclease 3'-5' domain-containing protein 2, EXD2, C14orf114, EXDL2

Background: Exonuclease required for double-strand breaks resection and efficient homologous recombination. Plays a key role in controlling the initial steps of chromosomal break repair, it is recruited to chromatin in a damage-dependent manner and functionally interacts with the MRN complex to accelerate resection through its 3'-5' exonuclease activity, which efficiently processes double-stranded DNA substrates containing nicks.

Gene ID: 55218

UniProt: Q9NVH0