ICAM-3/CD50 antibody (AA 30-203)
Quick Overview for ICAM-3/CD50 antibody (AA 30-203) (ABIN5684110)
Target
See all ICAM-3/CD50 (ICAM3) AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Binding Specificity
- AA 30-203
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Purpose
- CD50 Antibody
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Purification
- Purified antibody
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Immunogen
- Purified recombinant fragment of human CD50 (AA: 30-203) expressed in E. Coli.
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Isotype
- IgG1
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Application Notes
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ELISA: 1/10000
FCM: 1/200 - 1/400
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C,-20 °C
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Storage Comment
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- ICAM-3/CD50 (ICAM3) (Intercellular Adhesion Molecule 3 (ICAM3))
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Alternative Name
- CD50
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Background
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The protein encoded by this gene is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin-like C2-type domains, and bind to the leukocyte adhesion LFA-1 protein. This protein is constitutively and abundantly expressed by all leucocytes and may be the most important ligand for LFA-1 in the initiation of the immune response. It functions not only as an adhesion molecule, but also as a potent signalling molecule. Alternative splicing results in multiple transcript variants encoding different isoforms.
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Molecular Weight
- 59.5 kDa
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Gene ID
- 3385
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UniProt
- P32942
Target
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