LAIR1 antibody (AA 22-165)

Catalog No. ABIN5684133

This Mouse Monoclonal antibody specifically detects LAIR1 in ELISA and FACS. It exhibits reactivity toward Human.

Quick Overview for LAIR1 antibody (AA 22-165) (ABIN5684133)

Target: LAIR1 (Leukocyte-Associated Immunoglobulin-Like Receptor 1 (LAIR1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This LAIR1 antibody is un-conjugated

Application: ELISA, Flow Cytometry (FACS)

Clone: 1G8B6

Product Details anti-LAIR1 Antibody

Binding Specificity: AA 22-165

Purpose: CD305 Antibody

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human CD305 (AA: 22-165) expressed in E. Coli.

Isotype: IgG1

Application Details

Application Notes:

ELISA: 1/10000

FCM: 1/200 - 1/400

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Target Details for LAIR1

Target: LAIR1 (Leukocyte-Associated Immunoglobulin-Like Receptor 1 (LAIR1))

Alternative Name: CD305

Background: The protein encoded by this gene is an inhibitory receptor found on peripheral mononuclear cells, including natural killer cells, T cells, and B cells. Inhibitory receptors regulate the immune response to prevent lysis of cells recognized as self. The gene is a member of both the immunoglobulin superfamily and the leukocyte-associated inhibitory receptor family. The gene maps to a region of 19q13.4 called the leukocyte receptor cluster, which contains at least 29 genes encoding leukocyte-expressed receptors of the immunoglobulin superfamily. The encoded protein has been identified as an anchor for tyrosine phosphatase SHP-1, and may induce cell death in myeloid leukemias. Alternative splicing results in multiple transcript variants.

Molecular Weight: 31.4 kDa

UniProt: Q6GTX8