P2RY2 antibody

Catalog No. ABIN5684146

Product Details anti-P2RY2 Antibody

Target: P2RY2 (Purinergic Receptor P2Y, G-Protein Coupled, 2 (P2RY2))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This P2RY2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC), Flow Cytometry (FACS), Neutralization (Neut)

Purification: purified

Immunogen: Purified recombinant fragment of human P2RY2 (AA: extra mix) expressed in E. coli.

Clone: 6H12F9

Isotype: IgG2b

Application Details

Application Notes: ELISA: 1:10000, WB: 1:500 - 1:2000, ICC: N/A, FCM: 1:200 - 1:400, IHC: N/A

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: 4°C, -20°C for long term storage

Target Details for P2RY2

Target: P2RY2 (Purinergic Receptor P2Y, G-Protein Coupled, 2 (P2RY2))

Alternative Name: P2RY2 (P2RY2 Products)

Synonyms: P2U1 antibody, P2Y2 antibody, HP2U antibody, P2RU1 antibody, P2U antibody, P2UR antibody, P2Y2R antibody, P2Y purinoceptor 2 antibody, purinergic receptor P2Y, G-protein coupled 2 antibody, purinergic receptor P2Y2 antibody, p2ry2 antibody, P2ry2 antibody, P2RY2 antibody

Background:

Description: The product of this gene belongs to the family of P2 receptors, which is activated by extracellular nucleotides and subdivided into P2X ligand-gated ion channels and P2Y G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor, found on many cell types, is activated by ATP and UTP and is reported to be overexpressed on some cancer cell types. It is involved in many cellular functions, such as proliferation, apoptosis and inflammation. Three transcript variants encoding the same protein have been identified for this gene.

Aliases: P2U, HP2U, P2U1, P2UR, P2Y2, P2RU1, P2Y2R

Molecular Weight: 42.3 kDa

Gene ID: 5029

HGNC: 953

Pathways: Cellular Response to Molecule of Bacterial Origin, Smooth Muscle Cell Migration