C1QA antibody (FITC)

Catalog No. ABIN568566

The FITC-conjugated Goat Polyclonal anti-C1QA antibody (ABIN568566) specifically detects C1QA in IP, IF, IHC (fro), EIA and ID. The antibody is reactive with Human samples.

Quick Overview for C1QA antibody (FITC) (ABIN568566)

Target: C1QA (Complement Component 1, Q Subcomponent, A Chain (C1QA))

Reactivity: Human

Host: Goat

Clonality: Polyclonal

Conjugate: This C1QA antibody is conjugated to FITC

Application: Immunoprecipitation (IP), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro)), Enzyme Immunoassay (EIA), Immunodiffusion (ID)

Product Details anti-C1QA Antibody (FITC)

Specificity: Tested in Immunoelectrophoresis and Double Radial Immunodiffusion against normal Human serum, a single precipitin line is obtained which gives a reaction of full identity with the isolated immunogen. The product does not react with any other proteins component of Human serum or plasma. Inter-species cross-reactivity is a normal feature of antibodies to plasma proteins since they frequently share antigenic determinants. Cross-reactivity of this antiserum has not been tested in detail.

Characteristics: Absorption / Emission: 492 nm / 515 nm
Molar Ratio: Fluorescein/IgG ~ 1.8

Purification: The IgG fraction is isolated and purified from the antiserum and contains the bulk of the defined antibody specificity. It is free of other serum proteins as tested by Immunoelectrophoresis and double Radial Immunodiffusion.

Immunogen: The subunit C1q is isolated as a homogenous protein for use in antiserum production. Freund’s complete adjuvant is used in the first step of the immunization.

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Reconstitution: Restore by adding 1 mL of sterile distilled water.

Concentration: 10.8 mg/mL

Buffer: PBS, pH 7.2 without preservatives.

Preservative: Without preservative

Handling Advice: Avoid Repeated thawing and freezing.

Storage: 4 °C/-20 °C

Storage Comment: Store lyophilized at 2-8 °C and reconstituted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for C1QA

Target: C1QA (Complement Component 1, Q Subcomponent, A Chain (C1QA))

Alternative Name: C1q A Subunit

Background: C1 component of human complement is a complex of three glycoproteins: C1q, C1r and C1s. C1q has a molecular weight of 492.000 and is present in plasma in an average concentration of 80 mg/mL. It consists of a complex of 18 polypeptide chains of three different types, A, B and C, 6 of each type. The subcomponent C1q is responsible for the binding of C1q to immuno-complexes an membranes via the Fc portion of the immunoglobulin.Synonyms: Complement 1q, Complement C1q

Gene ID: 712

NCBI Accession: NP_057075

UniProt: P02745

Pathways: Complement System