NEFL antibody

Catalog No. ABIN5687476

The Chicken Polyclonal anti-NEFL antibody is suitable to detect NEFL in samples from Human, Rat, Mouse, Cow and Chicken. It has been validated for WB and IHC.

Quick Overview for NEFL antibody (ABIN5687476)

Target: NEFL (Neurofilament, Light Polypeptide (NEFL))

Reactivity: Human, Rat, Mouse, Cow, Chicken

Host: Chicken

Clonality: Polyclonal

Conjugate: This NEFL antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-NEFL Antibody

Specificity: Specific for the ~68k Neurofilament L protein in Western blots and works well on frozen sections, cells in tissue culture and on mildly formalin fixed histological sections.

Purification: Total IgY fraction

Immunogen: Preparation of bovine spinal cord intermediate filaments

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Storage: -20 °C

Storage Comment: Neurofilament NF-L antibody can be stored at -20°C and is stable at -20°C for at least 1 year.

Target Details for NEFL

Target: NEFL (Neurofilament, Light Polypeptide (NEFL))

Alternative Name: Neurofilament NF-L

Background: Neurofilaments are the 10nm or intermediate filament proteins found specifically in neurons, and are composed predominantly of three major proteins called NF-L, NF-M and NF-H. NF-L is the neurofilament light or low molecular weight polypeptide and runs on SDS-PAGE gels at about 68 kDa. Antibodies to NF-L are useful for identifying neuronal cells and their processes in tissue sections and in tissue culture. Mutations in the protein coding region of the human NF-L gene cause some forms of Charcot-Marie-Tooth disease.

Molecular Weight: 68 kDa

Gene ID: 4747

UniProt: P07196