Retinoic Acid Receptor gamma antibody (N-Term)

Catalog No. ABIN5688662

Product Details anti-Retinoic Acid Receptor gamma Antibody

Target: Retinoic Acid Receptor gamma (RARG) (Retinoic Acid Receptor, gamma (RARG))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Dog, Goat

Host: Mouse

Clonality: Monoclonal

Conjugate: This Retinoic Acid Receptor gamma antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Protein G purified

Immunogen: Peptide corresponding to amino acids from N-terminal region of human retinoic acid receptor, b-isotype.

Clone: 336

Isotype: IgG1

Application Details

Application Notes: The antibody has been directly tested for reactivity in Western blots in human tissues. It is anticipated that the antibody will also work with canine, guinea pig, mouse and rat tissues based on the fact that these species have 100 % homology with the amino acid sequence used as antigen.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: 100 μLin 10 mM HEPES (  pH 7.5), 150 mM NaCl, 100 μg per mL BSA and 50 % glycerol.

Storage: -20 °C

Storage Comment: Retinoic Acid Receptor antibody can be stored at -20°C and is stable at -20°C for at least 1 year.

Target Details for Retinoic Acid Receptor gamma

Target: Retinoic Acid Receptor gamma (RARG) (Retinoic Acid Receptor, gamma (RARG))

Alternative Name: Retinoic Acid Receptor (RARG Products)

Synonyms: NR1B3 antibody, RARC antibody, AI385767 antibody, Nr1b3 antibody, RARD antibody, RARgamma2 antibody, RARG antibody, etID309710.23 antibody, etID33387.23 antibody, rarg antibody, rarg2 antibody, wu:fb01e02 antibody, wu:fb01f03 antibody, wu:fc35a09 antibody, nr1b3 antibody, RARgamma-B antibody, retinoic acid receptor gamma antibody, retinoic acid receptor, gamma antibody, retinoic acid receptor gamma a antibody, retinoic acid receptor gamma S homeolog antibody, retinoic acid receptor, gamma b antibody, RARG antibody, Rarg antibody, rarga antibody, rarg.S antibody, rargb antibody

Background: Retinoic Acid (RA, active metabolite of vitamin A) plays a prominent role in regulating the transition of proliferating precursor cells (such as carcinoma cells and neuronal precursors) to postmitotic differentiated cells (Joshi et al., 2005). The Retinoid X receptors (RXRs) family (RXRalpha, beta and gamma) preferentially bind 9-cis-RA and regulate gene transcription by forming heterodimers with a second family of RA receptors (RARs). RAs have been suggested to potentially play a therapeutic role in cervical cancer (Abu et al., 2005). RAs are known to play key roles in neuronal development and an increasing body of evidence indicates that retinoid signaling may regulate synaptic plasticity and associated learning and memory behaviors (Lane and Bailey, 2005).

Molecular Weight: 48 kDa

Gene ID: 5915

UniProt: P10826

Pathways: Nuclear Receptor Transcription Pathway, Retinoic Acid Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Cell Size