Retinoid X Receptor antibody
The Mouse Monoclonal anti-Retinoid X Receptor antibody is suitable to detect Retinoid X Receptor in samples from Human, Mouse, Rat and Cow. It has been validated for WB.
Catalog No. ABIN5688670
$742.50
Plus shipping costs $50.00
100 μL
Shipping to:
United States
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Quick Overview for Retinoid X Receptor antibody (ABIN5688670)
Target
Retinoid X Receptor
Reactivity
Human, Mouse, Rat, Cow
Host
Mouse
Clonality
Monoclonal
Application
Western Blotting (WB)
Clone
1373
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Purification
- Protein G purified
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Immunogen
- Hinge peptide from human retinoid X receptor, y-isotype.
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Isotype
- IgG1
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Application Notes
- The antibody has been directly tested for reactivity in Western blots in human tissues. It is anticipated that the antibody will also work with bovine, mouse, non-human primate and rat tissues based on the fact that these species have 100 % homology with the amino acid sequence used as antigen.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- 100 μLin 10 mM HEPES ( pH 7.5), 150 mM NaCl, 100 μg per mL BSA and 50 % glycerol.
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Storage
- -20 °C
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Storage Comment
- Retinoid X Receptor antibody can be stored at -20°C and is stable at -20°C for at least 1 year.
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- Retinoid X Receptor
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Background
- Retinoic acid (RA, active metabolite of vitamin A) plays a prominent role in regulating the transition of proliferating precursor cells (such as carcinoma cells and neuronal precursors) to postmitotic differentiated cells (Joshi et al., 2005). The Retinoid X Receptors (RXRs) family (RXRalpha, beta and gamma) preferentially bind 9-cis-RA and regulate gene transcription by forming heterodimers with a second family of RA receptors. RAs have been suggested to potentially play a therapeutic role in cervical cancer (Abu et al., 2005). RAs are known to play key roles in neuronal development and an increasing body of evidence indicates that retinoid signaling may regulate synaptic plasticity and associated learning and memory behaviors (Lane and Bailey, 2005).
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Molecular Weight
- 48 kDa
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Gene ID
- 6258
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UniProt
- P48443
Target
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