NEFL antibody
Quick Overview for NEFL antibody (ABIN5688750)
Target
See all NEFL AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Specificity
- Specific for the ~68k Neurofilament L protein.
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Purification
- Total IgG fraction
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Immunogen
- Preparation of porcine intermediate filaments.
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Isotype
- IgG1
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Storage
- -20 °C
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Storage Comment
- Neurofilament NF-L antibody can be stored at -20°C and is stable at -20°C for at least 1 year.
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- NEFL (Neurofilament, Light Polypeptide (NEFL))
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Alternative Name
- Neurofilament NF-L
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Background
- Neurofilaments are the 10nm or intermediate filament proteins specifically in neurons, and are composed predominantly of three major proteins called NF- NF-M and NF-H. NF-L is the neurofilament light or low molecular weight polypeptide and runs on SDS-PAGE gels at about 68 kDa. Antibodies to NF-L are useful for identifying neuronal cells and their processes in tissue sections and in tissue culture. Mutations in the protein region of the human NF-L gene cause some forms of Charcot-Marie-Tooth disease.
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Molecular Weight
- 68 kDa
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Gene ID
- 4747
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UniProt
- P07196
Target
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