SNAP25 antibody (C-Term)
Quick Overview for SNAP25 antibody (C-Term) (ABIN5688859)
Target
See all SNAP25 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- C-Term
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Purification
- Affinity Purified
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Immunogen
- Peptide corresponding to amino acid residues from the C-terminal region of rat SNAP25 conjugated to keyhole limpet hemocyanin (KLH).
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- 100 μLin 10 mM HEPES ( pH 7.5), 150 mM NaCl, 100 μg per mL BSA and 50 % glycerol.
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Storage
- -20 °C
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Storage Comment
- SNAP25 antibody can be stored at -20°C and is stable at -20°C for at least 1 year.
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- SNAP25 (Synaptosomal-Associated Protein, 25kDa (SNAP25))
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Alternative Name
- SNAP25
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Background
- SNAP25 (Synaptosomal associated protein of 25 kDa) is a presynaptic plasma membrane protein that is widely distributed throughout the brain and involved in the regulation of neurotransmitter release. Decreased levels of SNAP25 have been found in the brains of patients with Down Syndrome and Alzheimer's Disease (Greber et al.,1999). In addition, a significant reduction in the hippocampal expression of SNAP25 has also been found in patients with Schizophrenia (Fatemi et al., 2001).
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Molecular Weight
- 25 kDa
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Gene ID
- 25012
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UniProt
- P60881
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Pathways
- Positive Regulation of Peptide Hormone Secretion, Hormone Transport, Synaptic Vesicle Exocytosis, Dicarboxylic Acid Transport
Target
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