DDC antibody (N-Term)

Catalog No. ABIN5688877

The Rabbit Polyclonal anti-DDC antibody has been validated for WB. It is suitable to detect DDC in samples from Human, Rat, Cow, Dog, Rabbit, Sheep and Goat.

Quick Overview for DDC antibody (N-Term) (ABIN5688877)

Target: DDC (Dopa Decarboxylase (Aromatic L-Amino Acid Decarboxylase) (DDC))

Reactivity: Human, Rat, Cow, Dog, Rabbit, Sheep, Goat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DDC antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-DDC Antibody

Binding Specificity: N-Term

Purification: Affinity Purified

Immunogen: Peptide from N-terminus region of human DOPA decarboxylase (DDC), conjugated to keyhole limpet hemocyanin (KLH).

Application Details

Application Notes: The antibody has been directly tested for reactivity in Western blots in bovine, canine, guinea pig, human, rabbit, rat and sheep tissues.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: 100 μLin 10 mM HEPES (  pH 7.5), 150 mM NaCl, 100 μg per mL BSA and 50 % glycerol.

Storage: -20 °C

Storage Comment: DOPA Decarboxylase antibody can be stored at -20°C and is stable at -20°C for at least 1 year.

Target Details for DDC

Target: DDC (Dopa Decarboxylase (Aromatic L-Amino Acid Decarboxylase) (DDC))

Alternative Name: DOPA Decarboxylase

Background: DOPA decarboxylase (aromatic L-amino acid decarboxylase, AADC, DDC) catalyzes the second reaction in the biosynthesis of catecholamines and serotonin (Waymire and Haycock, 2002, Berry et al., 1996, Haycock et al., 2003). It is also involved in the biosynthesis of trace amines. DDC antibodies can therefore be used as markers for dopaminergic, noradrenergic and serotonergic neurons in a variety of applications including depression, schizophrenia, Parkinson's disease and drug abuse (Kish et al., 2001, Zhu et al., 2000, Zhu et al., 1999).

Molecular Weight: 55 kDa

Gene ID: 1644

UniProt: P20711

Pathways: Dopaminergic Neurogenesis