EIF4B antibody (AA 420-424)
Quick Overview for EIF4B antibody (AA 420-424) (ABIN5689266)
Target
See all EIF4B AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 420-424
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Specificity
- This antibody detects endogenous level of total eIF4B protein.
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Purification
- Antibodies were purified by affinity-chromatography using epitope-specific peptide.
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Immunogen
- eIF4B (Ab-422) antibody was raised against a peptide sequence around aa.420~424 (T-G-S-E-S) derived from Human eIF4B.
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Application Notes
- Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Store antibody at -20°C for up to one year.
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- EIF4B (Eukaryotic Translation Initiation Factor 4B (EIF4B))
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Alternative Name
- eIF4B
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Background
- Required for the binding of mRNA to ribosomes. Functions in close association with EIF4-F and EIF4-A. Binds near the 5'-terminal cap of mRNA in presence of EIF-4F and ATP. Promotes the ATPase activity and the ATP-dependent RNA unwinding activity of both EIF4-A and EIF4-F.
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Molecular Weight
- 80 kDa
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Gene ID
- 1975
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NCBI Accession
- NP_001408
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UniProt
- P23588
Target
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