Doublecortin antibody (AA 413-417)

Catalog No. ABIN5689407

This Rabbit Polyclonal antibody specifically detects Doublecortin in WB. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for Doublecortin antibody (AA 413-417) (ABIN5689407)

Target: Doublecortin (DCX)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Doublecortin antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Doublecortin Antibody

Binding Specificity: AA 413-417

Specificity: This antibody detects endogenous level of total Doublecortin protein.

Purification: Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Immunogen: Doublecortin antibody was raised against a peptide sequence around aa.413~417 ( P-T-S-P-G) derived from Human Doublecortin.

Application Details

Application Notes: Western Blot: 1:500~1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+),  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store antibody at -20°C for up to one year.

Target Details for Doublecortin

Target: Doublecortin (DCX)

Alternative Name: Doublecortin

Background: Seems to be required for initial steps of neuronal dispersion and cortex lamination during cerebral cortex development. May act by competing with the putative neuronal protein kinase DCAMKL1 in binding to a target protein. May in that way participate in a signaling pathway that is crucial for neuronal interaction before and during migration, possibly as part of a calcium ion-dependent signal transduction pathway. May be part with LIS-1 of an overlapping, but distinct, signaling pathways that promote neuronal migration.

Molecular Weight: 40 - 45 kDa

Gene ID: 1641

NCBI Accession: NP_000546

UniProt: O43602