Cofilin antibody (AA 1-5)

Catalog No. ABIN5689443

This Rabbit Polyclonal antibody specifically detects Cofilin in WB and IHC. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for Cofilin antibody (AA 1-5) (ABIN5689443)

Target: Cofilin (CFL1) (Cofilin 1 (CFL1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Cofilin antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-Cofilin Antibody

Binding Specificity: AA 1-5

Specificity: This antibody detects endogenous level of total cofilin protein.

Purification: Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Immunogen: cofilin (Ab-3) antibody was raised against a peptide sequence around aa. 1~5 (M-A-S-G-V) derived from Human cofilin.

Application Details

Application Notes: Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+),  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store antibody at -20°C for up to one year.

Target Details for Cofilin

Target: Cofilin (CFL1) (Cofilin 1 (CFL1))

Alternative Name: cofilin

Background: Controls reversibly actin polymerization and depolymerization in a  pH -sensitive manner. It has the ability to bind G- and F-actin in a 1:1 ratio of cofilin to actin. It is the major component of intranuclear and cytoplasmic actin rods.

Molecular Weight: 19 kDa

Gene ID: 1072

NCBI Accession: NP_000213

UniProt: P23528

Pathways: Regulation of Cell Size, Tube Formation, Protein targeting to Nucleus, CXCR4-mediated Signaling Events