Fibrillarin antibody (AA 297-301)

Catalog No. ABIN5689460

This anti-Fibrillarin antibody is a Rabbit Polyclonal antibody detecting Fibrillarin in WB. Suitable for Human, Rat and Mouse.

Quick Overview for Fibrillarin antibody (AA 297-301) (ABIN5689460)

Target: Fibrillarin (FBL)

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Fibrillarin antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Fibrillarin Antibody

Binding Specificity: AA 297-301

Specificity: This antibody detects endogenous level of total Fibrillarin protein.

Purification: Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Immunogen: Fibrillarin antibody was raised against a peptide sequence around aa.297~301 ( L-T-L-E-P) derived from Human Fibrillarin.

Application Details

Application Notes: Western Blot: 1:500~1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+),  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store antibody at -20°C for up to one year.

Target Details for Fibrillarin

Target: Fibrillarin (FBL)

Alternative Name: Fibrillarin

Background: Involved in pre-rRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in pre-ribosomal RNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA.

Molecular Weight: 37 kDa

Gene ID: 2091

NCBI Accession: NP_001427

UniProt: P22087

Pathways: Ribonucleoside Biosynthetic Process