ASH2L antibody (AA 620-624)

Catalog No. ABIN5689522

The Rabbit Polyclonal anti-ASH2L antibody has been validated for WB. It is suitable to detect ASH2L in samples from Human, Mouse and Rat.

Quick Overview for ASH2L antibody (AA 620-624) (ABIN5689522)

Target: ASH2L (Set1/Ash2 Histone Methyltransferase Complex Subunit ASH2 (ASH2L))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ASH2L antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-ASH2L Antibody

Binding Specificity: AA 620-624

Specificity: This antibody detects endogenous level of total ASH2L protein.

Purification: Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Immunogen: ASH2L antibody was raised against a peptide sequence around aa.620~624 (G-R-R-S-P) derived from Human ASH2L.

Application Details

Application Notes: Western Blot: 1:500~1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+),  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store antibody at -20°C for up to one year.

Target Details for ASH2L

Target: ASH2L (Set1/Ash2 Histone Methyltransferase Complex Subunit ASH2 (ASH2L))

Alternative Name: ASH2L

Background: Component of the Set1/Ash2 histone methyltransferase (HMT) complex, a complex that specifically methylates 'Lys-4' of histone H3, but not if the neighboring 'Lys-9' residue is already methylated. As part of the MLL1/MLL complex it is involved in methylation and dimethylation at 'Lys-4' of histone H3. May function as a transcriptional regulator. May play a role in hematopoiesis.

Molecular Weight: 65, 80 kDa

Gene ID: 9070

NCBI Accession: NP_004665

UniProt: Q9UBL3