PSMC5 antibody

Catalog No. ABIN5689865

This anti-PSMC5 antibody is a Rabbit Polyclonal antibody detecting PSMC5 in WB and ELISA. Suitable for Human, Mouse, Rat, Zebrafish (Danio rerio), Dog, Drosophila melanogaster and C. elegans.

Quick Overview for PSMC5 antibody (ABIN5689865)

Target: PSMC5 (Proteasome (Prosome, Macropain) 26S Subunit, ATPase, 5 (PSMC5))

Reactivity: Human, Mouse, Rat, Zebrafish (Danio rerio), Dog, Drosophila melanogaster, C. elegans

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PSMC5 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-PSMC5 Antibody

Purification: Antibody is purified by protein A chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human PSMC5.

Application Details

Application Notes: PSMC5 antibody can be used for detection of PSMC5 by ELISA at 1:312500. PSMC5 antibody can be used for detection of PSMC5 by western blot at 1.25 μ,g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 100 μ,L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Storage: 4 °C,-20 °C

Storage Comment: For short periods of storage (days) store at 4°C. For longer periods of storage, store PSMC5 antibody at -20°C. As with any antibody avoid repeat freeze-thaw cycles.

Target Details for PSMC5

Target: PSMC5 (Proteasome (Prosome, Macropain) 26S Subunit, ATPase, 5 (PSMC5))

Alternative Name: PSMC5

Background: The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits.PSMC5 is one of the ATPase subunits, a member of the triple-A family of ATPases which have a chaperone-like activity. In addition to participation in proteasome functions, this subunit may participate in transcriptional regulation since it has been shown to interact with the thyroid hormone receptor and retinoid X receptor-alpha.

Molecular Weight: 46 kDa

Gene ID: 5705

NCBI Accession: NP_002796

UniProt: P62195

Pathways: Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA, Ubiquitin Proteasome Pathway