PSMC5 antibody

Catalog No. ABIN5689865

The Rabbit Polyclonal anti-PSMC5 antibody (ABIN5689865) specifically detects PSMC5 in WB and ELISA. The antibody is reactive with Human, Mouse, Rat, Zebrafish (Danio rerio), Dog, Drosophila melanogaster and C. elegans samples.

Quick Overview for PSMC5 antibody (ABIN5689865)

Target: PSMC5 (Proteasome (Prosome, Macropain) 26S Subunit, ATPase, 5 (PSMC5))

Reactivity: Human, Mouse, Rat, Zebrafish (Danio rerio), Dog, Drosophila melanogaster, C. elegans

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PSMC5 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-PSMC5 Antibody

Purification: Antibody is purified by protein A chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human PSMC5.

Application Details

Application Notes: PSMC5 antibody can be used for detection of PSMC5 by ELISA at 1:312500. PSMC5 antibody can be used for detection of PSMC5 by western blot at 1.25 μ,g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 100 μ,L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Storage: 4 °C,-20 °C

Storage Comment: For short periods of storage (days) store at 4°C. For longer periods of storage, store PSMC5 antibody at -20°C. As with any antibody avoid repeat freeze-thaw cycles.

Target Details for PSMC5

Target: PSMC5 (Proteasome (Prosome, Macropain) 26S Subunit, ATPase, 5 (PSMC5))

Alternative Name: PSMC5

Background: The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits.PSMC5 is one of the ATPase subunits, a member of the triple-A family of ATPases which have a chaperone-like activity. In addition to participation in proteasome functions, this subunit may participate in transcriptional regulation since it has been shown to interact with the thyroid hormone receptor and retinoid X receptor-alpha.

Molecular Weight: 46 kDa

Gene ID: 5705

NCBI Accession: NP_002796

UniProt: P62195

Pathways: Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA, Ubiquitin Proteasome Pathway