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DNAJC13 antibody (AA 1940-1990)

DNAJC13 Reactivity: Human, Mouse WB, ELISA, IHC (p) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN5689948
  • Target See all DNAJC13 products
    DNAJC13 (DnaJ heat shock protein family (Hsp40) member C13 (DNAJC13))
    Binding Specificity
    • 1
    • 1
    • 1
    • 1
    AA 1940-1990
    Reactivity
    • 3
    • 3
    • 1
    Human, Mouse
    Host
    • 3
    Rabbit
    Clonality
    • 3
    Polyclonal
    Conjugate
    • 3
    This DNAJC13 antibody is un-conjugated
    Application
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Specificity
    DNAJC13 antibody is human and mouse reactive. At least two siforms of DNAJC13 are known to exist, this antibody will detect both isoforms. DNAJC13 antibody is predicted to not cross-react with other DNAJC family members.
    Purification
    DNAJC13 antibody is affinity chromatography purified via peptide column.
    Immunogen
    DNAJC13 antibody was raised against an 18 amino acid peptide near the carboxy terminus of human DNAJC13.

    The immunogen is located within amino acids 1940 - 1990 of DNAJC13.
    Isotype
    IgG
  • Application Notes
    DNAJC13 antibody can be used for detection of DNAJC13 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    DNAJC13 antibody is supplied in PBS containing 0.02 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    DNAJC13 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
  • Target
    DNAJC13 (DnaJ heat shock protein family (Hsp40) member C13 (DNAJC13))
    Alternative Name
    DNAJC13 (DNAJC13 Products)
    Synonyms
    RME8 antibody, D030002L11Rik antibody, Gm1124 antibody, RME-8 antibody, Rme8 antibody, mKIAA0678 antibody, DnaJ heat shock protein family (Hsp40) member C13 antibody, dnaJ homolog subfamily C member 13 antibody, DNAJC13 antibody, LOC100167963 antibody, LOC100640734 antibody, Dnajc13 antibody
    Background
    DNAJC13, also known as receptor-mediated endocytosis 8 (RME8), is the human homolog to a DnaJ domain-containing protein originally identified in a screen for endocytic defects in C. elegans (1). It is thought to be a co-chaperone of Hsc70 which regulates protein conformation at membrane sites and plays a role in intracellular trafficking, co-localizing with markers of the endosomal system. Recent experiments have indicated that the DNAJC13 protein is involved in membrane trafficking through early endosomes but not through degradative organelles (2). DNAJC13 has been also been shown to regulate the intracellular trafficking of the epidermal growth factor receptor (3).
    Molecular Weight
    Predicted: 249 kDa

    Observed: 249 kDa
    Gene ID
    23317
    NCBI Accession
    NP_056083
    UniProt
    O75165
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