IL17RA antibody (AA 150-200)

Catalog No. ABIN5690002

The Rabbit Polyclonal anti-IL17RA antibody has been validated for WB, ELISA, IF and IHC (p). It is suitable to detect IL17RA in samples from Human, Mouse and Rat.

Quick Overview for IL17RA antibody (AA 150-200) (ABIN5690002)

Target: IL17RA (Interleukin 17 Receptor A (IL17RA))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IL17RA antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-IL17RA Antibody

Binding Specificity: AA 150-200

Specificity: IL-17RA antibody is human, mouse and rat reactive. Multiple isoforms of IL-17RA are known to exist. This antibody is predicted to not cross-react with other IL-17 receptor subunits.

Purification: IL-17RA Antibody is affinity chromatography purified via peptide column.

Immunogen: IL-17RA antibody was raised against an 18 amino acid peptide near the amino terminus of human IL-17RA.

The immunogen is located within amino acids 150 - 200 of IL-17RA.

Isotype: IgG

Application Details

Application Notes: IL-17RA antibody can be used for detection of IL-17RA by Western blot at 1 - 2 μ,g/mL.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: IL-17RA Antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: IL-17RA antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Target Details for IL17RA

Target: IL17RA (Interleukin 17 Receptor A (IL17RA))

Alternative Name: IL-17RA

Background: IL-17RA Antibody: Interleukin 17A (IL-17A) is a proinflammatory cytokine secreted by activated T-lymphocytes (1). It is a potent inducer of the maturation of CD34-positive hematopoietic precursors into neutrophils. IL-17RA is a ubiquitous type I membrane glycoprotein that binds with low affinity to IL-17A and IL-17F (1,2). IL-17A and its receptor play a pathogenic role in many inflammatory and autoimmune diseases such as rheumatoid arthritis (3,4). Defects in IL-17RA are the cause of familial candidiasis type 5 (CANDF5) which is a rare disorder with altered immune responses and impaired clearance of fungal infections (5).

Molecular Weight: Predicted: 95 kDa

Observed: 135 kDa

Gene ID: 23765

NCBI Accession: NP_055154

UniProt: Q96F46

Pathways: SARS-CoV-2 Protein Interactome