KIRREL3 antibody (AA 20-70)

Catalog No. ABIN5690032

Product Details anti-KIRREL3 Antibody

Target: KIRREL3 (Kin of IRRE Like 3 (KIRREL3))

Binding Specificity: AA 20-70

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KIRREL3 antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Specificity: KIRREL3 antibody is human, mouse and rat reactive. At least two isoforms are known to exist, this antibody will detect both isoforms. KIRREL3 antibody is predicted to not cross-react with other members of the KIRREL protein family.

Purification: KIRREL3 antibody is affinity chromatography purified via peptide column.

Immunogen: KIRREL3 antibody was raised against a 19 amino acid peptide near the amino terminus of human KIRREL3.

The immunogen is located within amino acids 20 - 70 of KIRREL3.

Isotype: IgG

Application Details

Application Notes: KIRREL3 antibody can be used for detection of KIRREL3 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: KIRREL3 antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: KIRREL3 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Target Details for KIRREL3

Target: KIRREL3 (Kin of IRRE Like 3 (KIRREL3))

Alternative Name: KIRREL3 (KIRREL3 Products)

Synonyms: KIRRE antibody, MRD4 antibody, NEPH2 antibody, PRO4502 antibody, 1500010O20Rik antibody, 2900036G11Rik antibody, SST4 antibody, mKIAA1867 antibody, kirre like nephrin family adhesion molecule 3 antibody, kin of IRRE like 3 (Drosophila) antibody, KIRREL3 antibody, Kirrel3 antibody

Background: KIRREL3, also known as nephrin-like protein 2, is a type I transmembrane protein belonging to a family of three podocin interacting proteins and the immunoglobulin superfamily (1). KIRREL3 is involved in the regulation of both glomerular and neural development (2), and more specifically, the nucleogenesis of the pontine nuclei in the developing hindbrain (3). KIRREL3 has also been shown to interact with the synaptic scaffold protein calmodulin-associated serine/threonine kinase (CASK) in neuronal cells (4).

Molecular Weight: Predicted: 64, 84 kDa

Observed: 60 kDa

Gene ID: 84623

NCBI Accession: NP_115920

UniProt: Q8IZU9