P4HB antibody

Catalog No. ABIN5690703

This Rat Monoclonal antibody specifically detects P4HB in ELISA and FACS. It exhibits reactivity toward Human.

Quick Overview for P4HB antibody (ABIN5690703)

Target: P4HB (Prolyl 4-Hydroxylase, beta Polypeptide (P4HB))

Reactivity: Human

Host: Rat

Clonality: Monoclonal

Conjugate: This P4HB antibody is un-conjugated

Application: ELISA, Flow Cytometry (FACS)

Clone: AIT 158D

Product Details anti-P4HB Antibody

Specificity: Recognizes human GITR. Does not cross-react with mouse GITR.

Immunogen: Recombinant human GITR.

Isotype: IgG2a kappa

Application Details

Application Notes: ELISA: (direct and indirect: 1:5,000-1:10,000). Flow Cytometry: (1:1,000). Optimal conditions must be determined individually for each application.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. 0.2um-filtered solution in PBS,  pH 7.4. Contains no preservatives.

Preservative: Without preservative

Storage: -20 °C

Storage Comment: Stable for at least 1 year after receipt when stored at -20°C.

Target Details for P4HB

Target: P4HB (Prolyl 4-Hydroxylase, beta Polypeptide (P4HB))

Alternative Name: GIT

Background: GITR is the receptor for TNFSF18. It is involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. Mediates NF-kappaB activation via the TRAF2/NIK pathway.

Gene ID: 8784

NCBI Accession: NP_004186

UniProt: Q9Y5U5

Pathways: Maintenance of Protein Location, Cell RedoxHomeostasis, Lipid Metabolism