Amylin/DAP antibody
Quick Overview for Amylin/DAP antibody (ABIN5691119)
Target
See all Amylin/DAP (IAPP) AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Isotype
- Ig Mix
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Application Notes
- Polyclonal anti-amylin is suitable for immunohistochemistry on frozen and paraffin-embedded tissues. Optimal antibody dilution should be determined by titration, recommended range is 1:800-1:1500 using PAP, or 1:300-1:500 using FITC, with over-night incubation at +4 °C.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Each vial contains 250 μL rabbit polyclonal antiserum containing 0.09 % sodium azide.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C,-20 °C
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Storage Comment
- Store at 4°C, or in small aliquots at -20°C.
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- Amylin/DAP (IAPP) (Islet Amyloid Polypeptide (IAPP))
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Alternative Name
- Amylin
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Background
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Amylin or islet amyloid polypeptide (IAPP) is produced in the pancreas beta cells and co-released with insulin. The amino acid sequence shows great homology with calcitonin gene related peptide (CGRP). Amylin has been shown to reverse insulin inhibition of hepatic gluconeogenesis and to inhibit muscle uptake of glucose.
Polyclonal anti-Amylin was obtained by immunizing a rabbit with human amylin. -
Pathways
- Hormone Activity, Feeding Behaviour
Target
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