IL18BP antibody (AA 29-193)

Catalog No. ABIN5692876

Product Details anti-IL18BP Antibody

Target: IL18BP (Interleukin 18 Binding Protein (IL18BP))

Binding Specificity: AA 29-193

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IL18BP antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Cross-Reactivity (Details): No cross reactivity with other proteins.

Characteristics: Rabbit IgG polyclonal antibody for IL18 binding protein detection. Tested with WB, ELISA(Cap) in Mouse,Rat.

Immunogen: E. coli-derived mouse IL18 binding protein recombinant protein (Position: T29-A193).

Application Details

Application Notes:

Recommended Detection Systems: Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ABIN921124) for Western blot.

Application Details: Western blot, 0.1-0.5 μg/mL
ELISA(Cap), 1-5 μg/mL

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na₂HPO₄, 0.05 mg NaN₃.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.

Target Details for IL18BP

Target: IL18BP (Interleukin 18 Binding Protein (IL18BP))

Alternative Name: Il18bp (IL18BP Products)

Synonyms: IL18BP antibody, IL-18BP antibody, Igifbp antibody, MC54L antibody, IL18BPa antibody, interleukin 18 binding protein antibody, IL18BP antibody, Il18bp antibody

Background:

Synonyms: Interleukin-18-binding protein, IL-18BP, Interferon gamma-inducing factor-binding protein, Il18bp, Igifbp

Background: Interleukin-18-binding protein is a protein that in humans is encoded by the IL18BP gene. The protein encoded by this gene functions as an inhibitor of the proinflammatory cytokine, IL18. It binds IL18, prevents the binding of IL18 to its receptor, and thus inhibits IL18-induced IFN-gamma production, resulting in reduced T-helper type 1 immune responses. This protein is constitutively expressed and secreted in mononuclear cells. Elevated level of this protein is detected in the intestinal tissues of patients with Crohn's disease. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

UniProt: Q9Z0M9