CD200 antibody (AA 31-231)

Catalog No. ABIN5693084

This anti-CD200 antibody is a Rabbit Polyclonal antibody detecting CD200 in WB and ELISA. Suitable for Human, Mouse and Rat.

Quick Overview for CD200 antibody (AA 31-231) (ABIN5693084)

Target: CD200

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CD200 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-CD200 Antibody

Binding Specificity: AA 31-231

Purpose: Anti-CD200/OX2 Antibody Picoband®

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Characteristics: Anti-/OX2 Antibody Picoband® (ABIN5693084). Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Immunogen: E. coli-derived human CD200/OX2 recombinant protein (Position: Q31-K231).

Isotype: IgG

Application Details

Application Notes: Western blot, 0.1-0.5 μg/mL
ELISA, 0.1-0.5 μg/mL
1. "Entrez Gene: CD200 CD200 Molecule". 2. Hoek RM, Ruuls SR, Murphy CA, et al. (2000). "Down-regulation of the macrophage lineage through interaction with OX2 (CD200)". Science. 290 (5497): 1768-71. 3. Wright GJ, Jones M, Puklavec MJ, et al. (2001). "The unusual distribution of the neuronal/lymphoid cell surface CD200 (OX2) glycoprotein is conserved in humans". Immunology. 102 (2): 173-9.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na₂HPO₄, 0.05 mg NaN₃.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Target Details for CD200

Target: CD200

Alternative Name: CD200

Background:

Synonyms: OX-2 membrane glycoprotein, CD200, MOX1, MOX2, My033

Tissue Specificity: Brain, heart, lung, kidney, placenta, pancreas, liver and skeletal muscle. Preferentially expressed in fetal brain.

Background: OX-2 membrane glycoprotein, also named CD200 (Cluster of Differentiation 200) is a human protein encoded by the CD200 gene. The protein encoded by this gene is a type-1 membrane glycoprotein, which contains two immunoglobulin domains, and thus belongs to the immunoglobulin superfamily. Studies of the related genes in mouse and rat suggest that this gene may regulate myeloid cell activity and delivers an inhibitory signal for the macrophage lineage in diverse tissues. Multiple alternatively spliced transcript variants that encode different isoforms have been found for this gene.

Molecular Weight: 45 kDa

Gene ID: 4345

UniProt: P41217