CEP68 antibody

Catalog No. ABIN5693149

The Rabbit Polyclonal anti-CEP68 antibody has been validated for WB. It is suitable to detect CEP68 in samples from Human, Mouse and Rat.

Quick Overview for CEP68 antibody (ABIN5693149)

Target: CEP68 (Centrosomal Protein 68kDa (CEP68))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CEP68 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CEP68 Antibody

Purpose: Anti-CEP68 Antibody Picoband®

Sequence: ELICWLYNVA DVTDHGTAAR SNLTSLKSSL QLYRQFKKDI D

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Characteristics: Anti-CEP68 Antibody Picoband® (ABIN5693149). Tested in WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human CEP68, which shares 73.2% and 75.6% amino acid (aa) sequence identity with mouse and rat EP68, respectively.

Isotype: IgG

Application Details

Application Notes: Western blot, 0.1-0.5 μg/mL
1. Fang, G., Zhang, D., Yin, H., Zheng, L., Bi, X., Yuan, L. Centlein mediates an interaction between C-Nap1 and Cep68 to maintain centrosome cohesion. J. Cell Sci. 127: 1631-1639, 2014. 2. Graser, S., Stierhof, Y.-D., Nigg, E. A. Cep68 and Cep215 (Cdk5rap2) are required for centrosome cohesion. J. Cell. Sci. 120: 4321-4331, 2007. 3. Man, X., Megraw, T. L., Lim, Y. P. Cep68 can be regulated by Nek2 and SCF complex. Europ. J. Cell Biol. 94: 162-172, 2015.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na₂HPO₄, 0.05 mg NaN₃.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Target Details for CEP68

Target: CEP68 (Centrosomal Protein 68kDa (CEP68))

Alternative Name: CEP68

Background:

Synonyms: Centrosomal protein of 68 kDa, Cep68, CEP68, KIAA0582

Tissue Specificity: Present in many fetal and adult tissues. Mainly expressed in adult skeletal muscle, thymus, testis, ovary, and pancreas, low or absent in brain and peripheral blood leukocytes.

Background: Centrosomal protein of 68 kDa is a protein that in humans is encoded by the CEP68 gene. It is mapped to chromosome 2. CEP68 is required for centrosome cohesion. It decorates fibres emanating from the proximal ends of centrioles. CEP68 and rootletin depend both on each other for centriole association, and both also require CEP250 for their function.

Molecular Weight: 81 kDa

Gene ID: 23177

UniProt: Q76N32

Pathways: SARS-CoV-2 Protein Interactome