STS antibody (AA 297-396)

Catalog No. ABIN5693165

Product Details anti-STS Antibody

Target: STS (Steroid Sulfatase (Microsomal), Isozyme S (STS))

Binding Specificity: AA 297-396

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This STS antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Brand: Picoband™

Cross-Reactivity (Details): No cross reactivity with other proteins.

Characteristics: Rabbit IgG polyclonal antibody for Steroid sulfatase detection. Tested with WB, Direct ELISA in Human,Mouse,Rat.

Immunogen: E. coli-derived human Steroid sulfatase recombinant protein (Position: K297-E396).

Application Details

Application Notes:

Recommended Detection Systems: Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ABIN921124) for Western blot.

Application Details: Western blot, 0.1-0.5 μg/mL
Direct ELISA, 0.1-0.5 μg/mL

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na₂HPO₄, 0.05 mg NaN₃.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.

Target Details for STS

Target: STS (Steroid Sulfatase (Microsomal), Isozyme S (STS))

Alternative Name: STS (STS Products)

Synonyms: ARSC antibody, ARSC1 antibody, ASC antibody, ES antibody, SSDD antibody, XLI antibody, abcg2 antibody, ArsC antibody, Sts antibody, si:ch211-271l9.1 antibody, steroid sulfatase antibody, breast cancer resistance protein antibody, Steryl-sulfatase antibody, steryl-sulfatase antibody, steroid sulfatase (microsomal), isozyme S antibody, STS antibody, abcg2 antibody, Sts antibody, Plav_0360 antibody, Psta_3963 antibody, Runsl_5106 antibody, LOC100712701 antibody, sts antibody

Background:

Synonyms: Steryl-sulfatase, Arylsulfatase C, ASC, Steroid sulfatase, Steryl-sulfate sulfohydrolase, STS, ARSC1

Background: Steroid sulfatase (STS), or steryl-sulfatase, formerly known as arylsulfatase C, is a sulfatase enzyme involved in the metabolism of steroids. It is encoded by the STS gene. This gene encodes a multi-pass membrane protein that is localized to the endoplasmic reticulum. It belongs to the sulfatase family and hydrolyzes several 3-beta-hydroxysteroid sulfates, which serve as metabolic precursors for estrogens, androgens, and cholesterol. Mutations in this gene are associated with X-linked ichthyosis (XLI). Alternatively spliced transcript variants resulting from the use of different promoters have been described for this gene.

UniProt: P08842

Pathways: Steroid Hormone Biosynthesis