BIRC2 antibody (AA 320-570)
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- Target See all BIRC2 Antibodies
- BIRC2 (Baculoviral IAP Repeat Containing 2 (BIRC2))
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Binding Specificity
- AA 320-570
- Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This BIRC2 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA
- Brand
- Picoband™
- Cross-Reactivity (Details)
- No cross reactivity with other proteins.
- Characteristics
- Rabbit IgG polyclonal antibody for cIAP1 detection. Tested with WB, Direct ELISA in Human,Mouse,Rat.
- Immunogen
- E. coli-derived human cIAP1 recombinant protein (Position: D320-T570).
- Top Product
- Discover our top product BIRC2 Primary Antibody
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- Application Notes
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Recommended Detection Systems: Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ABIN921124) for Western blot.
Application Details: Western blot, 0.1-0.5 μg/mL
Direct ELISA, 0.1-0.5 μg/mL - Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- Buffer
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
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At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.
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- Target
- BIRC2 (Baculoviral IAP Repeat Containing 2 (BIRC2))
- Alternative Name
- BIRC2 (BIRC2 Products)
- Synonyms
- API1 antibody, HIAP2 antibody, Hiap-2 antibody, MIHB antibody, RNF48 antibody, c-IAP1 antibody, cIAP1 antibody, Api2 antibody, rIAP1 antibody, IAP1 antibody, ITA antibody, AW146227 antibody, Api1 antibody, Birc3 antibody, HIAP1 antibody, IAP2 antibody, MIAP1 antibody, MIAP2 antibody, MIHC antibody, cIAP2 antibody, mcIAP1 antibody, ciap-1 antibody, birc3 antibody, api1 antibody, birc2 antibody, c-iap1 antibody, ciap1 antibody, hiap-2 antibody, hiap2 antibody, mihb antibody, rnf48 antibody, baculoviral IAP repeat containing 2 antibody, baculoviral IAP repeat-containing 2 antibody, baculoviral IAP repeat containing 2 L homeolog antibody, BIRC2 antibody, Birc2 antibody, birc2 antibody, birc2.L antibody
- Background
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Synonyms: Baculoviral IAP repeat-containing protein 2
Tissue Specificity: Present in many fetal and adult tissues. Mainly expressed in adult skeletal muscle, thymus, testis, ovary, and pancreas, low or absent in brain and peripheral blood leukocytes.
Background: Baculoviral IAP repeat-containing protein 2 (also known as cIAP1) is a protein that in humans is encoded by the BIRC2 gene.The protein encoded by this gene is a member of a family of proteins that inhibits apoptosis by binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2, probably by interfering with activation of ICE-like proteases. This encoded protein inhibits apoptosis induced by serum deprivation and menadione, a potent inducer of free radicals. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
- UniProt
- Q13490
- Pathways
- Apoptosis, Caspase Cascade in Apoptosis, Activation of Innate immune Response, Toll-Like Receptors Cascades
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