BIRC2 antibody (AA 320-570)

Catalog No. ABIN5693185

Product Details anti-BIRC2 Antibody

Target: BIRC2 (Baculoviral IAP Repeat Containing 2 (BIRC2))

Binding Specificity: AA 320-570

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BIRC2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Brand: Picoband™

Cross-Reactivity (Details): No cross reactivity with other proteins.

Characteristics: Rabbit IgG polyclonal antibody for cIAP1 detection. Tested with WB, Direct ELISA in Human,Mouse,Rat.

Immunogen: E. coli-derived human cIAP1 recombinant protein (Position: D320-T570).

Application Details

Application Notes:

Recommended Detection Systems: Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ABIN921124) for Western blot.

Application Details: Western blot, 0.1-0.5 μg/mL
Direct ELISA, 0.1-0.5 μg/mL

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na₂HPO₄, 0.05 mg NaN₃.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.

Target Details for BIRC2

Target: BIRC2 (Baculoviral IAP Repeat Containing 2 (BIRC2))

Alternative Name: BIRC2 (BIRC2 Products)

Synonyms: API1 antibody, HIAP2 antibody, Hiap-2 antibody, MIHB antibody, RNF48 antibody, c-IAP1 antibody, cIAP1 antibody, Api2 antibody, rIAP1 antibody, IAP1 antibody, ITA antibody, AW146227 antibody, Api1 antibody, Birc3 antibody, HIAP1 antibody, IAP2 antibody, MIAP1 antibody, MIAP2 antibody, MIHC antibody, cIAP2 antibody, mcIAP1 antibody, ciap-1 antibody, birc3 antibody, api1 antibody, birc2 antibody, c-iap1 antibody, ciap1 antibody, hiap-2 antibody, hiap2 antibody, mihb antibody, rnf48 antibody, baculoviral IAP repeat containing 2 antibody, baculoviral IAP repeat-containing 2 antibody, baculoviral IAP repeat containing 2 L homeolog antibody, BIRC2 antibody, Birc2 antibody, birc2 antibody, birc2.L antibody

Background:

Synonyms: Baculoviral IAP repeat-containing protein 2

Tissue Specificity: Present in many fetal and adult tissues. Mainly expressed in adult skeletal muscle, thymus, testis, ovary, and pancreas, low or absent in brain and peripheral blood leukocytes.

Background: Baculoviral IAP repeat-containing protein 2 (also known as cIAP1) is a protein that in humans is encoded by the BIRC2 gene.The protein encoded by this gene is a member of a family of proteins that inhibits apoptosis by binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2, probably by interfering with activation of ICE-like proteases. This encoded protein inhibits apoptosis induced by serum deprivation and menadione, a potent inducer of free radicals. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

UniProt: Q13490

Pathways: Apoptosis, Caspase Cascade in Apoptosis, Activation of Innate immune Response, Toll-Like Receptors Cascades