EOMES antibody (AA 310-532)

Catalog No. ABIN5693217

Product Details anti-EOMES Antibody

Target: EOMES (Eomesodermin (EOMES))

Binding Specificity: AA 310-532

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EOMES antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Brand: Picoband™

Cross-Reactivity (Details): No cross reactivity with other proteins.

Characteristics: Rabbit IgG polyclonal antibody for TBR2/Eomes detection. Tested with WB, Direct ELISA in Human,Mouse,Rat.

Immunogen: E. coli-derived human TBR2/Eomes recombinant protein (Position: T310-D532).

Application Details

Application Notes:

Recommended Detection Systems: Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ABIN921124) for Western blot.

Application Details: Western blot, 0.1-0.5 μg/mL
Direct ELISA, 0.1-0.5 μg/mL

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na₂HPO₄, 0.05 mg NaN₃.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.

Target Details for EOMES

Target: EOMES (Eomesodermin (EOMES))

Alternative Name: EOMES (EOMES Products)

Synonyms: TBR2 antibody, eom antibody, eomes antibody, EOMES antibody, xeomes antibody, tbr2 antibody, C77258 antibody, TBR-2 antibody, Tbr2 antibody, eomesodermin antibody, eomesodermin homolog a antibody, eomesodermin L homeolog antibody, EOMES antibody, eomesa antibody, Eomes antibody, eomes.L antibody, eomes antibody

Background:

Synonyms: Eomesodermin homolog, T-box brain protein 2, T-brain-2, TBR-2, EOMES, TBR2

Tissue Specificity: Expressed in CD8+ T-cells.

Background: Eomesodermin also known as T-box brain protein 2 (Tbr2) is a protein that in humans is encoded by the EOMES gene. This gene belongs to the TBR1 (T-box brain protein 1) sub-family of T-box genes that share the common DNA-binding T-box domain. The encoded protein is a transcription factor which is crucial for embryonic development of mesoderm and the central nervous system in vertebrates. The protein may also be necessary for the differentiation of effector CD8+ T cells which are involved in defense against viral infections. A similar gene disrupted in mice is shown to be essential during trophoblast development and gastrulation. Alternative splicing results in multiple transcript variants.

UniProt: O95936

Pathways: Stem Cell Maintenance