PLA2G6 antibody (AA 715-802)

Catalog No. ABIN5693280

Product Details anti-PLA2G6 Antibody

Target: PLA2G6 (Phospholipase A2, Group VI (Cytosolic, Calcium-Independent) (PLA2G6))

Binding Specificity: AA 715-802

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PLA2G6 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Cross-Reactivity (Details): No cross reactivity with other proteins.

Characteristics: Rabbit IgG polyclonal antibody for PLA2G6 detection. Tested with WB, Direct ELISA in Human,Mouse,Rat.

Immunogen: E. coli-derived human PLA2G6 recombinant protein (Position: W715-L802).

Application Details

Application Notes:

Recommended Detection Systems: Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ABIN921124) for Western blot.

Application Details: Western blot, 0.1-0.5 μg/mL
Direct ELISA, 0.1-0.5 μg/mL

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na₂HPO₄, 0.05 mg NaN₃.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.

Target Details for PLA2G6

Target: PLA2G6 (Phospholipase A2, Group VI (Cytosolic, Calcium-Independent) (PLA2G6))

Alternative Name: PLA2G6 (PLA2G6 Products)

Synonyms: zgc:77476 antibody, wu:fc06g09 antibody, PNPLA9 antibody, MGC83523 antibody, PLA2G6 antibody, BB112799 antibody, iPLA(2)beta antibody, iPLA2 antibody, iPLA2beta antibody, CaI-PLA2 antibody, GVI antibody, INAD1 antibody, IPLA2-VIA antibody, NBIA2 antibody, NBIA2A antibody, NBIA2B antibody, PARK14 antibody, PLA2 antibody, iPla2 antibody, phospholipase A2, group VI (cytosolic, calcium-independent) antibody, phospholipase A2 group VI antibody, phospholipase A2 group VI S homeolog antibody, 85/88 kDa calcium-independent phospholipase A2 antibody, phospholipase A2, group VI antibody, pla2g6 antibody, PLA2G6 antibody, pla2g6.S antibody, LOC100445065 antibody, Pla2g6 antibody

Background:

Synonyms: 85/88 kDa calcium-independent phospholipase A2, CaI-PLA2, Group VI phospholipase A2, GVI PLA2, Intracellular membrane-associated calcium-independent phospholipase A2 beta, iPLA2-beta, Patatin-like phospholipase domain-containing protein 9, PNPLA9, PLA2G6, PLPLA9

Tissue Specificity: Four different transcripts were found to be expressed in a distinct tissue distribution.

Background: 85 kDa calcium-independent phospholipase A2 is an enzyme that in humans is encoded by the PLA2G6 gene. The protein encoded by this gene is an A2 phospholipase, a class of enzyme that catalyzes the release of fatty acids from phospholipids. The encoded protein may play a role in phospholipid remodelling, arachidonic acid release, leukotriene and prostaglandin synthesis, fas-mediated apoptosis, and transmembrane ion flux in glucose-stimulated B-cells. Several transcript variants encoding multiple isoforms have been described, but the full-length nature of only three of them have been determined to date.

UniProt: O60733

Pathways: Positive Regulation of Peptide Hormone Secretion