PROX1 antibody (C-Term) (Biotin)

Catalog No. ABIN569680

This Rabbit Polyclonal antibody specifically detects PROX1 in IF. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for PROX1 antibody (C-Term) (Biotin) (ABIN569680)

Target: PROX1 (Prospero Homeobox 1 (PROX1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PROX1 antibody is conjugated to Biotin

Application: Immunofluorescence (IF)

Product Details anti-PROX1 Antibody (Biotin)

Binding Specificity: C-Term

Specificity: This antibody will detect Prox-1 in the nucleus of lymphatic endothelial cells.

Purification: Antigen-Affinity Chromatography.

Immunogen: Recombinant highly conserved C-terminal part of the homeobox transcription factor Human Prox1 (homeo domain and prospero domain).

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Reconstitution: Restore in sterile water to a concentration of > 0.5 mg/mL

Buffer: PBS, pH 7.4 without presrevatives and stabilizers.

Preservative: Without preservative

Handling Advice: This product is photosensitive and should be protected from light

Storage: 4 °C

Storage Comment: Prior to and following reconstitution store the antibody undiluted at 2-8 °C. DO NOT FREEZE!

Target Details for PROX1

Target: PROX1 (Prospero Homeobox 1 (PROX1))

Alternative Name: PROX-1

Background: Prox-1 is a homeobox gene and acts as a master switch for lymphatic endothelial phenotype. Expression of Prox-1 in blood endothelial cells induces expression of other lymphatic marker genes. Together with Podoplanin, Prox-1 can be used to reliably distinguish lympathic vessels from blood vessels. Prox1 is expressed in CNS, eye, pancreas, liver and heart, and it is one of the most specific and reliable markers for lymphatic endothelial cells.Synonyms: Homeobox prospero-like protein PROX1, PROX1, Prospero homeobox protein 1

Gene ID: 5629

NCBI Accession: NP_002754

UniProt: Q92786

Pathways: Stem Cell Maintenance, Regulation of Muscle Cell Differentiation