BMP2 antibody (AA 283-396)

Catalog No. ABIN5697155

The Rabbit Polyclonal anti-BMP2 antibody has been validated for WB, IHC and ELISA. It is suitable to detect BMP2 in samples from Human, Mouse, Rat and Pig.

Quick Overview for BMP2 antibody (AA 283-396) (ABIN5697155)

Target: BMP2 (Bone Morphogenetic Protein 2 (BMP2))

Reactivity: Human, Mouse, Rat, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BMP2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Product Details anti-BMP2 Antibody

Binding Specificity: AA 283-396

Purpose: BMP2 antibody

Immunogen:

Immunogen sequence: 283-396aa

Immunogen: bone morphogenetic protein 2

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1: 5000,IHC: 1:20-1:200,IF: 1:50-1:500

Comment:

HeLa cells were subjected to SDS PAGE followed by western blot with FNab00917(BMP2 antibody) at dilution of 1:100

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for BMP2

Target: BMP2 (Bone Morphogenetic Protein 2 (BMP2))

Alternative Name: BMP2

Background:

Synonyms: Bone morphogenetic protein 2 (BMP-2)|Bone morphogenetic protein 2A (BMP-2A)|BMP2|BMP2A

Background: Bone morphogenetic protein-2 (BMP-2) is a member of the transforming growth factor-beta (TGFB) superfamily. BMP2 is synthesized as a 60 kDa precursor that is processed in the secretory pathway to a small 18 kDa monomer, 2 monomers then associate to form the active 30 kDa homodimer, which binds to its receptor. There is also a 40-45 kDa form of BMP2, as an amino-terminal propeptide. BMP2 can induce bone formation and regeneration during early embryonic development. It is involved in the hedgehog pathway, TGF beta signaling pathway, and cytokine-cytokine receptor interaction.

Molecular Weight: 45 kDa

Gene ID: 650

UniProt: P12643

Pathways: Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Regulation of Muscle Cell Differentiation, Growth Factor Binding, Positive Regulation of fat Cell Differentiation