FKBP8 antibody

Catalog No. ABIN5697691

This Rabbit Polyclonal antibody specifically detects FKBP8 in WB and ELISA. It exhibits reactivity toward Human and Mouse.

Quick Overview for FKBP8 antibody (ABIN5697691)

Target: FKBP8 (FK506 Binding Protein 8, 38kDa (FKBP8))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FKBP8 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-FKBP8 Antibody

Purpose: FKBP8 antibody

Immunogen: FK506 binding protein 8, 38kDa

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for FKBP8

Target: FKBP8 (FK506 Binding Protein 8, 38kDa (FKBP8))

Alternative Name: FKBP8

Background:

Synonyms: Peptidyl-prolyl cis-trans isomerase FKBP8 (PPIase FKBP8)|38 kDa FK506-binding protein (38 kDa FKBP, FKBP-38, hFKBP38)|FK506-binding protein 8 (FKBP-8)|FKBPR38|Rotamase|FKBP8|FKBP38

Background: Constitutively inactive PPiase, which becomes active when bound to calmodulin and calcium. Seems to act as a chaperone for BCL2, targets it to the mitochondria and modulates its phosphorylation state. The BCL2/FKBP8/calmodulin/calcium complex probably interferes with the binding of BCL2 to its targets. The active form of FKBP8 may therefore play a role in the regulation of apoptosis.

Molecular Weight: 53 kDa

Gene ID: 23770

UniProt: Q14318

Pathways: Autophagy