HDAC8 antibody

Catalog No. ABIN5697854

The Rabbit Polyclonal anti-HDAC8 antibody is suitable to detect HDAC8 in samples from Human, Mouse and Rat. It has been validated for WB, ELISA and IP.

Quick Overview for HDAC8 antibody (ABIN5697854)

Target: HDAC8 (Histone Deacetylase 8 (HDAC8))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HDAC8 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunoprecipitation (IP)

Product Details anti-HDAC8 Antibody

Purpose: HDAC8 antibody

Immunogen: histone deacetylase 8

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for HDAC8

Target: HDAC8 (Histone Deacetylase 8 (HDAC8))

Alternative Name: HDAC8

Background:

Synonyms: Histone deacetylase 8 (HD8)|Protein deacetylase HDAC8|Protein decrotonylase HDAC8|HDAC8|HDACL1

Background: Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class I of the histone deacetylase family. It catalyzes the deacetylation of lysine residues in the histone N-terminal tails and represses transcription in large multiprotein complexes with transcriptional co-repressors. Multiple transcript variants encoding different isoforms have been found for this gene.

Molecular Weight: 49 kDa

Gene ID: 55869

UniProt: Q9BY41

Pathways: Cellular Glucan Metabolic Process