MCL-1 antibody

Catalog No. ABIN5697987

This anti-MCL-1 antibody is a Rabbit Polyclonal antibody detecting MCL-1 in WB, ELISA, IHC and IP. Suitable for Human, Mouse and Rat.

Quick Overview for MCL-1 antibody (ABIN5697987)

Target: MCL-1 (MCL1) (Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1 (MCL1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MCL-1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP)

Product Details anti-MCL-1 Antibody

Purpose: MCL1 antibody

Immunogen: myeloid cell leukemia sequence 1 (BCL2-related)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

Raji cells were subjected to SDS PAGE followed by western blot with FNab05052(MCL1 antibody) at dilution of 1:1000

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for MCL-1

Target: MCL-1 (MCL1) (Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1 (MCL1))

Alternative Name: MCL1

Background:

Synonyms: Induced myeloid leukemia cell differentiation protein Mcl-1|Bcl-2-like protein 3 (Bcl2-L-3)|Bcl-2-related protein EAT/mcl1|mcl1/EAT|MCL1|BCL2L3

Background: This gene encodes an anti- apoptotic protein, which is a member of the Bcl-2 family. Alternative splicing results in multiple transcript variants. The longest gene product (isoform 1) enhances cell survival by inhibiting apoptosis while the alternatively spliced shorter gene products (isoform 2 and isoform 3) promote apoptosis and are death-inducing.

Molecular Weight: 40 kDa

Gene ID: 4170

UniProt: Q07820

Pathways: MAPK Signaling